Although there are several controversial results on the cytokine profile in pemphigus, one systematic review of cytokine study in pemphigus reported increased levels of TNF‐α, TGF‐β, IL‐8, IL‐10, IL‐12, IL‐17, and IL‐21 and decreased levels of IL‐2 and IL‐23.24 The gene discussed is IL21; the disease is pemphigus.