Cancer and senescent cells also show common features that include overlapping signaling pathways, involving participation of tumor protein p53 (TP53), cyclin‐dependent kinase inhibitor 1A (CDKN1A/p21), ataxia–telangiectasia mutated (ATM), dephosphorylation of retinoblastoma (RB), and ROS (Rajendran et al., 2019). The gene discussed is CDKN1A; the disease is cancer.