Likely pathogenic variants in 12 of these 102 monogenic epilepsy genes were observed in 44 epileptic subjects: CHRNA4, CLN3, CLN8, DEPDC5, KCNJ10, KCNMA1, POLG, PRICKLE1, SCN1A, SCN2A, SCN8A and SCN9A. Of the 18 additional genes from Table 2 with likely pathogenic variants, a number including SZT2, SCN10A, UBA5 have been reported in whole-exome sequencing in epilepsy subjects [19, 20]. The gene discussed is POLG; the disease is epilepsy.