CCL11 and COVID-19: Neurotoxic CCL11 causes white matter selective microglial reactivity, then elevated CCL11 and active microglia lead to deleterious cascade effects on CNS multi-lineage neuronal cellular function and structure dysregulation, particularly on oligodendrocytes, myelinated axons, and hippocampal neurogenesis, which in turn causes the cognitive dysfunction symptoms in COVID-19 (Fig. 1).