Additionally, in HCC cells with endogenous SRSF10 depletion, forced exogenous SRSF10(WT) could sustain CDC25A(△E6) abundance, whereas SRSF10(△RRM) displayed no effects on exon 6 exclusion and remained responsive to SRSF10 deprivation (Fig. 2I). This evidence concerns the gene CDC25A and hepatocellular carcinoma.