KLF4 and osteosarcoma: To determine whether LINC00629 elevates the osteosarcoma cell adaption to ER stress and facilitates tumorigenesis by regulating the KLF4-LAMA4 axis, we first overexpressed LINC00629 in KLF4- or LAMA4-depleted MNNG/HOS cells and these cells were treated with 3 μM TM for 36 h.