Similarly, in the critical circulatory and respiratory diseases, the L/A ratio showed superiority in predicting the prognosis of critical illness than lactate and albumin (circulatory disease: L/A ratio 0.825, lactate 0.804, albumin 0.763; respiratory disease: L/A ratio 0.661, lactate 0.636, and albumin 0.613) (Figs. 2B and C). The gene discussed is ALB; the disease is respiratory system disorder.