GJA1 and breast cancer: On the contrary, miR-492 was not associated with Cx43 loss, as it was not differentially expressed in Cx43-KO-S1 compared to S1 miRNome, and was up-regulated at all grades of the malignancy in the breast cancer database, but only in the young patients below the age of 40 in the Lebanese population, suggesting that it might be acting upstream of Cx43 loss/mis-localization and epithelial polarity disruption, especially in the young Lebanese patient cohort.