Interestingly, all the genes of the pathway were significantly downregulated in the tumor samples, except for the Branched-Chain Amino Acid Transaminase 1 (BCAT1) and the lysosomal amino acids oxidase Interleukin 4 Induced 1 (IL4I1), which were strongly upregulated (Fig. 1b). This evidence concerns the gene BCAT1 and neoplasm.