Abdominal entry and intestinal manipulation can compromise splanchnic perfusion and lead to mucosal barrier dysfunction, predisposing to postoperative complications.26In support of these observations, reduced intestinal permeability, endotoxemia, and interleukin (IL)-6 formation have been observed in patients undergoing RP compared with TP repair.27, 28. The gene discussed is IL6; the disease is serum lipopolysaccharide activity.