However, it has been reported that the expression level of FLT3 on THP-1 is higher than that on MV4-11 and MOLM-3 [25], while the sensitivity of ASP1235 on THP-1 was poorer compared to MV4-11 and MOLM-13 (Figure 1), suggesting that FLT3 expression level does not always reflect the cytotoxic activity of ASP1235 on leukemia cells. The gene discussed is FLT3; the disease is leukemia.