NAV3 and primary cutaneous T-cell non-Hodgkin lymphoma: Other gain of function mutations seen in CTCL include Nav3 (12q21), JunB (chr19), c-MYC/MAX, p53, PTEN/Fas, p15, p16, NFKB, bcl-2, and Stat2.The mutations in CTCL are still being studies and as of now there are more than 500 chromosomal abnormalities, including TCR signalling and chromatin modification, noted in CTCL.