Interestingly, we found that overexpressed METTL3 alleviated the inhibitory impact of ATT on proliferation, migration and invasion, in addition to the apoptosis‐inducing effect of ATT in RA‐FLSs (Figure 7G–L), implying that ATT might affect METTL3 to regulate ICAM2 expression in RA‐FLSs. Here, ICAM2 is linked to rheumatoid arthritis.