To determine whether G0S2 is mechanistically involved in TKI resistance or strictly a biomarker, we lentivirally transduced CML cell lines and patient samples for G0S2 ectopic expression using two separate vectors, and confirmed G0S2 upregulation by immunoblot analyses and/or RT‐qPCR (Figure S3A,B). The gene discussed is G0S2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.