CD4 and systemic lupus erythematosus: To further study the association between DNMT3a, H3K4me3, and SUV39H1 in the CREMα promoter region of SLE CD4+ T cells, the quantities of DNMT3a and H3K4me3 in the region of CD4+ T cells from the aforementioned cohort were measured by ChIP combined with qPCR.