PPOX and infection: Moreover, several complement component associated protein genes were significantly altered in mRNA abundance with infection, including several C-type lectins (CTL1, CTL4, CTL6, CTL12) and another complement-like protein (LOC725964) in 3 dpi larvae, which have a potential role in opsonization of pathogens and possibly contributing to a PPO activation, a melanization/nodulation reaction and haemocyte-associated cellular defence [45].