The modulation of c-MYC expression, monitored at the mRNA level, was further investigated by western blot confirming a robust protein downregulation not only in NB4 cells, but also in other hematopoietic neoplasm cellular models (HL-60, K562, Jurkat, and U937—Fig. 6D). This evidence concerns the gene MYC and hematopoietic and lymphoid cell neoplasm.