KLK3 and posterior cortical atrophy: Finally, patients with a score between 95 and 150 were identified as being in the medium-risk group and had to be actively monitored through follow-up MRI and PSA assessments.Using the XYFY risk model, unnecessary biopsies could be avoided in nearly 49% of patients (195/394), while missing only 3.0% (6/201) of PCa patients.