SRSF1 and Miyoshi myopathy: Overexpression of SRSF1 led to a significant increase in MM cell proliferation compared to control cells in vitro (Fig. 3F) and impacted overall survival in vivo, where mice injected with SRSF1 overexpressing cells had a median survival of 53 days while mice injected with empty control cells had a median survival of 77 days (Fig. 3G).