We observed RNA binding motifs (RBM) for 38 SFs, including multiple motifs from SRSF1, SRSF9, FXR2, PCBP2, and RBM5 (Fig. 2A and Supplementary Table 5 for RSAT results), which were significantly enriched around the regions alternatively spliced in MM cells. Here, RBM5 is linked to Miyoshi myopathy.