We observed inhibition of cell growth (assessed by 3H-thymidine uptake; Fig. 3A and Supplementary Fig. 4B) and MM cell viability (measured by CellTiter-Glo; Fig. 3B) compared to scramble control as well as shRNA #93, which failed to KD SRSF1 protein. The gene discussed is SRSF1; the disease is Miyoshi myopathy.