Even though ATP11A’s involvement in obesity and T2D is unknown, there is evidence that deficient expression of some P4 ATPase family members, such as ATP10C and ATP10A, affects insulin-stimulated mobilization of GLUT4 vesicles to the plasma membrane or the regulation of insulin signaling [43]. Here, SLC2A4 is linked to obesity due to melanocortin 4 receptor deficiency.