ENPP2 and pseudotumor cerebri: The mechanism of the autotaxin molecule in patients with IIH indicates that H2O2may be increased probably due to inflammation in the adipose tissue, and that the increase in the autotaxin level may be for the purpose of protecting microglial cells.26In addition, the cytokines released by the autotaxin product LPA cause the autotaxin molecule to be oversynthesized.