KCNK1 and pancreatic adenocarcinoma: Thus, the high level of KCa3.1 channel mRNA and the inverse TWIK-1 and TASK-3 transcript expression compared to normal pancreatic tissue may be related to their evolution as pancreatic adenocarcinoma cells, and therefore, Capan-1 grown as epithelium may also have limitations concerning pancreatic duct physiology.