Furthermore, multivariate analysis of these eight factors showed that pLN metastasis (HR = 2.259, 95% CI: 1.191–4.285, p = 0.013), molecular subtype (HR = 1.776, 95% CI: 1.013–3.113, p = 0.045), and RMI2 expression (HR = 2.528, 95% CI: 1.165–5.486, p = 0.019) were independent risk factors for poor prognosis of breast cancer (Table 2). The gene discussed is RMI2; the disease is breast carcinoma.