Miro1 acts in well studied biological pathways in PD, interacting with PINK1, Parkin, LRRK2 and α-synuclein (Wang et al., 2011; Birsa et al., 2014; Hsieh et al., 2016; Klosowiak et al., 2016; Shaltouki et al., 2018) and is an important marker of PINK1-Parkin mediated mitophagy and mitochondrial morphogenesis (Hsieh et al., 2019; Konig et al., 2021; Lopez-Domenech et al., 2021). This evidence concerns the gene RHOT1 and Parkinson disease.