The KALRN gene has been linked to neurodevelopmental disorder risk, with mutations in KALRN implicated in schizophrenia (Kushima et al., 2012; Purcell et al., 2014; Russell et al., 2014, 2018; Howrigan et al., 2020), ASD (Leblond et al., 2019; Satterstrom et al., 2020), developmental delay (Deciphering Developmental Disorders Study, 2017), and intellectual disability linked to hereditary homozygous loss of KALRN-expression (Makrythanasis et al., 2016). The gene discussed is KALRN; the disease is Intellectual disability.