Another lncRNA, named 91H which located at the H19/IGF2 locus and transcribed in H19 antisense orientation, is overexpressed in breast cancer and prevent the maternal allele at the H19/IGF2 locus from DNA methylation, by this mechanism to induce overexpression of oncogenic H19 (Vennin et al., 2017). The gene discussed is IGF2; the disease is breast cancer.