The lncRNA TTTY15 could interact with DNMT3A and prevent its binding to TBX4 promoter in non-small cell lung cancer (NSCLC), the lower expression level of TTTY15 and the associated downregulation of TBX4 is connected with metastasis and worse prognosis of NSCLC patients (Lai et al., 2019). This evidence concerns the gene TBX4 and non-small cell lung carcinoma.