MAGI2 and breast carcinoma: For example, lncRNA MAGI2-AS3 (MAGI2 antisense RNA 3) which is transcribed from the antisense strand near the MAGI2, acts as cis-acting factor to downregulate the DNA methylation level of the MAGI2 promoter by interaction with TET1 and promotes apoptosis by activating the Fas/FasL signaling pathway in breast cancer (Xu et al., 2021).