Alagarasu et al. found in a Western Indian population that HLA-B*18 was significantly positively associated with both combined DHF/DF and DF infection versus HC (P<0.05) (OR=3.53 and 95% CI=0.87-20.43; OR=2.12 and 95% CI=0.99-4.52) [14]. This evidence concerns the gene HLA-B and dengue disease.