The functional mechanism of these lncRNAs in tumor cells involves a variety of cell signaling pathways related to cellular processes, such as p53, nuclear transcription factor-κB (NF-κB), phosphatidyl inositol 3-kinase (PI3K)/protein kinase B (AKT), extracellular regulated protein kinases (ERK)/mitogen-activated protein kinase (MAPK), wingless-type MMTV integration site family (Wnt)/β-chain protein (β-catenin), and hypoxia-inducible factor-1α (HIF1α) (Peng et al., 2017). The gene discussed is AKT1; the disease is neoplasm.