Notably, PBI-05204 alone significantly affected the in vivo tumor growth of RD by 44% ± 3.9% (Figure 7A, RD, PBI-05204 vs. Untreated) and of RH30 by 52.1% ± 7.1% (Figure 7A, RH30, PBI-05204 vs. Untreated). Here, RHD is linked to neoplasm.