NRIP1, a coregulator of several nuclear receptors and transcription factors, can act as a co-activator or corepressor and is upregulated in a variety of tumor types, including gastric cancer (Liang and Li, 2020), gastric adenocarcinoma (Fang and Lu., 2020), esophageal squamous cell carcinoma (Ni et al., 2018), and breast cancer (Binato et al., 2021). This evidence concerns the gene NRIP1 and gastric adenocarcinoma.