NRIP1, a coregulator of several nuclear receptors and transcription factors, can act as a co-activator or corepressor and is upregulated in a variety of tumor types, including gastric cancer (Liang and Li, 2020), gastric adenocarcinoma (Fang and Lu., 2020), esophageal squamous cell carcinoma (Ni et al., 2018), and breast cancer (Binato et al., 2021). The gene discussed is NRIP1; the disease is breast carcinoma.