Pyruvate dehydrogenase kinase 1 (PDK1), which could inactivate PDH and is an independent risk factor for NSCLC, is highly expressed in tumor tissues of NSCLC patients, and its overexpression promotes the proliferation and metastasis of NSCLC (Liu and Yin, 2017). This evidence concerns the gene PDK1 and non-small cell lung carcinoma.