MKI67 and neoplasm: In well differentiated OSCC (n=19), the expression was located mainly at the periphery of the tumor nests than in the center, and most of these cases (n=15; 78.9%) showed low Ki-67 expression, while all poorly differentiated OSCC cases (n=20) showed high Ki-67 expression that was detected at the periphery of and at the tumor nests.