NFKB1 and metabolic dysfunction-associated steatotic liver disease: Intragastric NaB (500 mg/kg/day) and/or Clostridium butyricum (5*107 CFU/kg/day) for 6 weeks of treatment in db/db mice (with T2D-induced NAFLD) along with a Caco-2 cell culture supported the downregulation of the TLR-4/MyD88/NF-kB pathway, and the improvement was more significant in the group receiving Clostridium butyricum (25).