LPS has the capacity of binding to Toll-like receptors (TLRs) of the cell as well as activating various downstream signaling pathways, leading to the synthesis of interleukin (IL)-1β, tumor necrosis factor alpha (TNF-α), IL-6, and other proinflammatory cytokines (Wells et al., 2009; Chunhua et al., 2022) Not only can they arouse an inflammatory response and launch fever in infected bodies, but also promote the adhesion of endothelial cells and white blood cells via regulating the expression of adhesion molecules, thus leading to collateral damage to tissues and even septicemia. This evidence concerns the gene TNF and Sepsis.