Cytochrome P450 family 11 subfamily B member 1 (CYP11B1 gene) is located on chromosome 8q24.3 and encodes the steroid 11 β-hydroxylase, which influences the synthesis of aldosterone and activates cellular pathways to promote hypertension and cardiovascular disease (Hussain and Awan, 2018). The gene discussed is CYP11B1; the disease is Hypertension.