CYP26B1 is associated with skeletal abnormalities in humans and zebrafish (Laue et al., 2011) and CYP26B1 knockouts produced reduced limbs in mice (Yashiro et al., 2004), while EXOC6B is associated with spondyloepimetaphyseal dysplasia in humans which symptoms include skeletal malformations affecting the long bones of the limbs and short stature (Campos‐Xavier et al., 2018). The gene discussed is CYP26B1; the disease is spondyloepimetaphyseal dysplasia, matrilin-3 type.