Interestingly, certain single nucleotide polymorphisms (SNPs) in CSF2RB are associated with inflammatory responses like reaction to mosquito bites and with immune-mediated diseases and autoimmunity including eczema, allergy, inflammatory bowel disease (IBD) and MS, which indicates a crucial role for CSF2RB in various diseases (12). The gene discussed is CSF2RB; the disease is allergic disease.