Xiaoqiang Qi et al.’s study of the therapeutic effect of Minimally invasive radiofrequency ablation (RFA) combined with sunitinib in an HCC model showed that the combined treatment increased the frequency of CD8+ T cells and DCs, reduced Tregs infiltration, and activated tumor-specific antigen (TSA) immune response, ultimately favoring inhibition of HCC growth (177). Here, CD8A is linked to hepatocellular carcinoma.