Furthermore, TIICs, including activated CD8 and CD4 T cells, effector memory CD8 T cells, and type 17 Th cells, were enriched in the low-m5C-score subgroup, whereas the infiltrating levels of pro-tumor immune cells (plasmacytoid dendritic cells) were significantly higher in the high-m5C-score group (Supplementary Figure 6A). Here, CD4 is linked to neoplasm.