Conversely, no differences in the percentages of responding CD4+ T-cells neither in the percentages of triple-positive T-cells in both pwMS and HD were found (responding CD4+ T-cells: 1.23 [0.60-1.63] and 1.03 [0.80-1.28], respectively; triple-positive CD4+ T-cells: 0.09 [0.03-0.09] and 0.05 [0.03-0.09], respectively; triple-positive CD8+ T-cells: 0.06 [0.03-0.10] and 0.05 [0.02-0.09], respectively) (Figure 3B, C). The gene discussed is CD8A; the disease is Huntington disease.