TNFSF13 and Huntington disease: At T0, a higher plasma level of APRIL in both the depleting/sequestering-out and the enriching-in subgroups compared to HD was observed (the depleting/sequestering-out: 12603 [8077-19540] and 832.70 [220.10-3042] pg/ml, respectively, p=0.0005; the enriching-in: 15312 [9740-11670] and 832.70 [220.10-3042] pg/ml, respectively, p=0.0017) (Figure 4E).