And cDC-CD1C-AREG sub-cluster in high tumor infiltration group expressed low level of genes mentioned above, including HLA–B, HLA-C, HLA-DRB1, HLA-DQA1, IL1B, VEGF and CCL4, which like the unstimulated cDC-CD1C-AREG in HD (Figure 5E). This evidence concerns the gene HLA-B and neoplasm.