This was further supported by the high levels of MHC I/II molecules (HLA–B, HLA-C, HLA-DRB1 and HLA-DQA1) expressed in cDC-CD1C-AREG from low tumor infiltration group as well as inflammatory cytokines and chemokines (IL1B, VEGF and CCL4, etc.) (Figure 5E). Here, IL1B is linked to neoplasm.