Microarray profiles of 50 BCC samples in one study showed that CAV-1 gene expression was upregulated; they proposed that CAV-1 may play a dynamic role in controlling the slow progression of BCC by decreasing cellular motility since CAV-1 is known to inhibit epidermal growth factor-induced migration in other cell types (11, 39). This evidence concerns the gene CAV1 and skin basal cell carcinoma.