A strong correlation between Anti-Carbamethylated Protein (CarP) antibody levels and both clinical and ultrasonographic activity was described (correlation between anti-CarP and DAS-28 (r=0.96), CRP (r=0.97), ESR (r=0.97) and US power Doppler+synovitis with a Pearson coefficient >0.97) (96). The gene discussed is CRP; the disease is synovitis.