CFLAR and glioblastoma: Moreover, the comparisons of enriched pathways among GBM subgroups show that a number of oncogenic and immune-associated pathways are significantly upregulated in MES, such as I-kappaB kinase/NF-kappaB signaling, regulation by c-FLIP, extracellular matrix organization, NOD-like receptor signaling pathway, Toll-like receptor signaling pathway, and leukocyte transendothelial migration.