PIM1 and chronic myelogenous leukemia, BCR-ABL1 positive: It was reported that, however, in blast crisis chronic myelogenous leukemia (CML-BC), apart from targeting mRNA encoding the survival factor PIM1, restoration of miR-328 can also interact with the translational regulator poly (rC) -binding protein hnRNP E2 and then leads to release of CEBPA mRNA from hnRNP E2-mediated translational inhibition.