ADAMTS13 and thrombotic thrombocytopenic purpura: Particularly since ADAMTS-13 antigens and vaccine components (including SARS-CoV-2-spike (S) proteins) bear no resemblance, and the autoimmune process (the formation of autoreactive B-cells, plasma cells, and autoantibodies) and development of the clinical phenotype of TTP requires at least 7-10 days (33).