PP2A-related neurodevelopmental disorders (NDDs) are a group of rare genetic diseases characterized by heterozygous de novo mutations in PPP2CA (Reynhout et al., 2019) (OMIM: #618354), PPP2R1A (Houge et al., 2015; Lenaerts et al., 2020; Douzgou et al., 2022) (OMIM: #616362), or PPP2R5D (Houge et al., 2015; Loveday et al., 2015; Shang et al., 2016; Mirzaa et al., 2019; Oyama et al., 2022) (OMIM: #616355). This evidence concerns the gene PTPA and neurodevelopmental disorder.