MIF and myocardial infarction: It was found that loading the macrophage migration inhibitory factor (MIF) into human umbilical cord blood MSC-derived Exos, known as MIF-Exo, increased proliferation and angiogenesis in the human umbilical vein endothelial cells (HUVEC) and inhibited apoptosis, showing good cardioprotective effects in an acute myocardial infarction rat model (Zhu et al., 2021).