In tumor tissues, drastic reductions in MNs (-103x) and CATs (-1671x) concentrations were observed in NB as compared to PHEO/PGL, with 0.53 versus 54.9 nmol/g for MNs and 5.4 versus 8992 nmol/g for CATs, respectively (Figure 1 and Supplementary Figures 1C-D). Here, PIMREG is linked to neoplasm.