Furthermore, specific RA characteristics, such as increasing joint deformity, patient-reported disability scores, elevated c-reactive protein (CRP) concentrations, rheumatoid factor seropositivity, and a lack of current treatment with disease-modifying antirheumatic drugs (DMARDs) were associated with abnormal body composition phenotypes.31 Ecici32 noted that 31.5% of the newly diagnosed, treatment-naive patients with RA exhibited sarcopenia, with a greater prevalence among men. The gene discussed is CRP; the disease is rheumatoid arthritis.